Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This can be an impurity relevant to bortezomib, a proteasome inhibitor Employed in the cure of many myeloma. Its synthesis or examine is critical for guaranteeing the purity and security from the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor within the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound in the synthesis of imatinib, a drug that targets precise sorts of most cancers, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats different cancers for example breast, lung, and prostate most cancers.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): These are definitely intermediates while in the synthesis of gemcitabine, an anti-cancer drug. Their analyze is essential for optimizing the output method and making certain higher purity.
Lapatinib Intermediate (CAS NO. 231278-84-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist used in the remedy of breast cancer. Different intermediates assist in the synthesis of the drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers such as ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the remedy of colorectal cancer and smaller mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-9): 3-Hydroxy-1-aminoadamantane This compound is involved in the synthesis of adamantane derivatives, which have several purposes, which includes antiviral Homes.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for style 2 diabetes that inhibits the enzyme DPP-4 to control blood sugar levels.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-one): This compound is involved in the synthesis of various gluconic acid derivatives, that are used in food, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate two: A precursor in the synthesis of canagliflozin, a medication used to deal with style 2 diabetes by CAS NO. 302964-08-5 inhibiting sodium-glucose co-transporter two (SGLT2).